國立成功大學生命科學系

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陳虹樺特聘教授

陳虹樺特聘教授

    特聘教授

    電話:+886-6-275-7575 ext. 65521

    email: hhchen@mail.ncku.edu.tw

    <English Version>

研究專長: 1. 蘭花生物科技學 2. 基因體學與生物資訊 3. 分子生物學 4. 細胞生物學

研究方向1. Hz-1病毒的功能基因體分析及其演化定位 2.蝴蝶蘭花部功能基因體分析

學歷

  • 博士,微生物系密西根州立大學
  • 學士,生物系,國立臺灣師範大學


現職:

服務機關 職稱 起迄年月
國立成功大學 生命科學系 特聘教授 自 2007/08   迄今 
國立成功大學 蘭花研究中心 主任 自 2009/12   迄今

經歷

服務機關 職稱 起迄年月
國立成功大學 熱帶植物科學研究所 所長 自 2009/08  至2012/07
國立成功大學 生物科學與科技學院   代理院長 自 2009/08  至2010/07
中央研究院   植物研究所 研究員 自 2004/02  至2005/01  
中央研究院   植物研究所 訪問學者 自 2003/08  至2004/01
國立成功大學 生命科學系 教授 自 2001/08  至2007/07
國立成功大學  農業生物技術研究中心 副主任 自 2000/04  至2002/07 
法國Perpignan大學   植物基因體及植物生理研究所 訪問學者 自 1998/10  至1999/02
國立成功大學  生物科技研究所 副教授 自 1998/08  至2001/07 
國立成功大學  生物學系(所)   副教授 自 1994/08  至2001/07
中央研究院    分子生物研究所   博士後研究 自 1991/12  至1994/07
台北縣立碧華國中  教師 自1982 至 1985


榮譽與獎勵

榮獲「國立成功大學特聘教授」獎項 2007年~迄今
榮獲 科技部103年度傑出研究獎  104.3.26
成大蘭花研究團隊與國際團隊合作完成 全世界第一個全基因體解序的蘭科植物,這篇研究論文「The genome sequence of the orchid Phalaenopsis equestris」刊登於2014年11月24日Nature Genetics期刊,並獲選為封面文章。103年11月
榮獲「國立成功大學鼓勵發表國際頂尖期刊獎勵」獎項
榮獲「發展國際一流大學及頂尖研究中心計畫」研究及產學合作優良教 師及研究人員--B級獎勵
榮獲「產學合作研究進步獎勵」

榮獲中央研究院植物研究所 蕭介夫老師實驗室

中研院短期訪問研究 92.08.01~ 93.01.31

 
新聞報導:

論文著述:

論文(click)

A. 期刊論文

  1.  Hsu, C.C., Chen, Y.Y., Tsai, W.C., Chen, W.H., and Chen, H.H.* 2015. Trio of R2R3-MYB transcription factors regulate floral pigmentation patterning in Phalaenopsis orchids. Plant Physiology (First revision)
  2. Cai, J., Liu, X., Vanneste, K., Proost, S., Tsai, W.C., Liu, K.W., Li-Jun Chen1, He, Y., Xu, Q., Bian, C., Zheng, Z., Sun, F., Liu, W., Hsiao, Y.Y., Pan, Z.J., Hsu, C.C., Yang, Y.P., Hsu, Y.C., Chuang, Y.C., Dievart, A., Dufayard, J.F., Xu, X., Wang, J.Y., Wang, J., Xiao, X.J., Zhao, X.M., Du, R., Zhang, G.Q., Wang, M., Su, Y.Y., Xie, G.C., Liu, G.H., Li, L.Q., Huang, L.Q., Luo, Y.B., Chen, H.H. *, Van de Peer, Y., and Liu, Z.J. 2015. The genome sequence of the orchid Phalaenopsis equestrisNature Genetics 47, 65-72.
  3. Hsieh, M.H., Pan, Z.J., Yeh, H.H., and Chen, H.H.* 2014. Virus-induced gene silencing in Phalaenopsis. Bio-Protocol 4, 1-9.
  4. Hsu, C.C., Wu, P.S., Chen, T.C., Tsai, W.C., Wu, K., Wu, W.L., Chen, W.H., and Chen, H.H.* 2014. Histone acetylation accompanied with promoter sequences displaying differential expression profiles of B-class MADS-box genes for Phalaenopsis floral morphogenesis. PLoS ONE 9, e106033. doi:10.1371/journal.pone.0106033
  5. Pan, Z.J., Chen, Y.Y., Du, J.S., Chen, Y.Y., Chung, M.C., Tsai, W.C., Wang, C.N., and Chen, H.H.* 2014, May. Flower development of Phalaenopsis orchid involves functionally divergent SEPALLATA-like genes. New Phytologist 202, 1024-1042.
  6.  Hsieh, M.H., Lu, H.C., Yeh, H.H., Pan, Z.J., Wang, S.S., Chen, W.H., and Chen, H.H.* 2013, September. Virus-induced gene silencing unravels multiple transcription factors involved in floral growth and development in Phalaenopsis orchids. Journal of Experimental Botany 64, 3869-3884.
  7. Hsiao, Y.Y., Huang, T. S., Fu, C.H., Huang, S.C., Chen, Y.J., Huang, Y.M., Chen, W.H., Tsai, W.C., and Chen, H.H.* 2013, April. Transcriptomic analyses of floral organs of Phalaenopsis orchid by oligonucleotide microarray. Gene 518, 91-100.
  8. Hsieh, M.H., Lu, H.C., Yeh, H.H., Pan, Z.J., Wang, S.S., Chen, W.H., and Chen, H.H.* 2013, March. Optimizing virus-induced gene silencing efficacy with Cymbidium mosaic virus in Phalaenopsis flowerPlant Science 201-202, 25-41.
  9. Tsai, W.C., Fu, C.H., Hsiao, Y.Y., Huang, Y.M., Chen, L.J., Wang, M., Liu, J.J., and Chen, H.H.* 2013, February. OrchidBase 2.0: comprehensive collection of Orchidaceae floral transcriptomes. Plant and Cell Physiology 54, e7.
  10. Chen, J.C., Lu, H.C., Chen, C.E., Hsu, H.F., Chen, H.H., and Yeh, H.H.* 2013, January. The NPR1 ortholog PhaNPR1 is required for the induction of PhaPR1 in Phalaenopsis AphroditeBotanical Studies 54, 31.
  11.  Chang, C.H., Wang, H.I., Lu, H.C., Chen, C.E., Chen, H.H., Yeh, H.H., Tang, C.Y.* 2012, September. An efficient RNA interference screening strategy for gene functional analysis. BMC Genomics 13, 491.
  12. Lu H.C., Hsieh, M.H., Chen, C.E., Chen, H.H., Wang, H.I., and Yeh, H.H.* 2012, June. A high-throughput virus-induced gene-silencing vector for screening transcription factors in virus-induced plant defense response in orchid. Molecular Plant-Microbe Interactions 25, 738-746.
  13. Hsiao, Y.Y., Pan, Z.J., Hsu, C.C., Yang, Y.P., Hsu, Y.C., Chuang, Y.C., Shih, S.H., Chen, W.H., Tsai, W.C., and Chen, H.H.* 2011, September. Researches on orchid biology and biotechnology. Plant and Cell Physiology 52, 1467-1486.
  14. Pan, Z.J., Cheng, C.C., Tsai, W.C., Chung, M.C., Chen, W.H., Hu, M.J., and Chen, H.H.* 2011, September. The duplicated B-class MADS-box genes display dualistic characters in orchid floral organ identity and growth. Plant and Cell Physiology 52, 1515-1531.
  15. Tsai, W.C., Huang, S.C., Chen, Y.W., Hsiao, Y.Y., Pan, Z.J., and Chen, H.H.* 2011, July. Gene discovery using next generation pyrosequencing to develop ESTs for Phalaenopsis orchids. BMC Genomics 12, 360. (97-2317-B-006-002-)
  16. Chen, W.H., Hsu, C. Y., Cheng, H.Y., Chang H., Chen, H.H., and Ger, M.J.* 2011, June. Downregulation of putative UDP-glucose: flavonoid3-O-glucosyltransferase gene alters flower coloring in PhalaenopsisPlant Cell Report 30, 1007-1017.
  17. Fu, C.H., Chen, Y.W., Hsiao, Y.Y., Pan, Z.J., Liu, Z.H., Huang, Y.M., Tsai, W.C., and Chen, H.H.* 2011, February. OrchidBase: A collection of sequences of transcriptome derived from orchids. Plant and Cell Physiology 52, 238-243.
  18. Hsu, C.C., Chung, Y.L., Lee, Y.L., Kuo, Y.T., Chen, T.C., Tsai, W.C., Hsiao, Y.Y., Chen, W.H., Wu, W. L., and Chen, H.H.* 2011, January. An overview of the Phalaenopsis orchid genome through BAC end sequence analysis. BMC Plant Biology 11, 3.
  19. Lin, X.C., Chow, T.Y., Chen, H.H., Liu, C.C., Chou, S.J., Huang, B.L., Kuo, C. I., Wen, C.K., Huang, L.C., and Fang, W.* 2010, June. Understanding bamboo flowering based on large-scale analysis of expressed sequence tags. Genetic and Molecular Research 9, 1085-1093.
  20.  Wu, Y.L., Wu, C.P., Lee, S.T., Tang, H., Chang, C.H., Chen, H.H., and Chao, Y.C.* 2010, January. The early gene hhi1 functions in the reactivation of latent HzNV-1 virus. Journal of Virology 84, 1057-1065.

B.研討會論文

  1. Lee M.C., Chuang, Y.C., and Chen, H.H.* 2014.The effect of light on the floral scent emission in Phalaenopsis orchids. December 13~14. Innovation and Translational Technologies in Plant Sciences. Taipei, Taiwan.

  2. Hung, Y.C., Chuang, Y.C., and Chen, H.H.* 2014. Development of molecular markers for floral scent from the GDPS promoter sequence in Phalaenopsis orchids. December 13~14. Innovation and Translational Technologies in Plant Sciences. Taipei, Taiwan.

  3. Lai, P.H., Hsu, C.C., Tsai, W.C., and Chen, H.H.* 2014. Analysis of transposable elements during micropropagation of Phalaenopsis orchids. December 13~14. Innovation and Translational Technologies in Plant Sciences. Taipei, Taiwan.

  4. Chuang, Y.C. and Chen, H.H.* 2014. Transcriptomic analysis of terpenoid biosynthesis genes to reveal its regulation mechanism in Phalaenopsis bellina. December 13~14. Innovation and Translational Technologies in Plant Sciences. Taipei, Taiwan. 

  5. Chen, H.H.* 2014. Orchid genomics and functional genomics. International Symposium of Plant Floral Development and Physiology, October 20, Tainan, Taiwan.
  6. Hsu, C.C., Tsai, W. C., Hsiao, Y.Y., Picault, N., Panaud, O., and Chen, H.H.* 2013. Identification of retrotransposon/transposon in Phalaenopsis equestris genome. Plant Biology and Plant Breeding, French Taiwanese Workshop, October 23-24, Font-Romeu, France.
  7. Hsieh, M.H., and Chen, H.H.* 2013. Virus-induced gene silencing unravels multiple transcription factors involved in floral growth and development in Phalaenopsis orchids. Workshop on Molecular Mechanisms Controlling Flwoer Development. June 8-12. Presqu'ile de Giens, Cote D'azur, France.
  8. Pan Z. J., and Chen, H.H.* 2013. Identification and characterization of E-class SEP-like MADS-box genes in Phalaenopsis orchids. Workshop on Molecular Mechanisms Controlling Flwoer Development. June 8-12. Presqu'ile de Giens, Cote D'azur, France.
  9. Hsieh, M.H., Lu, H.C., Yeh, H.H., Pan, Z.J., Wang, S.S., Chen, W.H., and Chen, H.H.* 2013. Optimizing virus-induced gene silencing efficacy with Cymbidium mosaic virus in Phalaenopsis flower. May 17-19. 5th International Orchid Workshop: Orchid population dynamics. University of Calabria, Rende, Italy.

  10. Hsiao, Y.Y., Yang, Y.P., and Chen, H.H.* 2013. Floral scent production in Phalaenopsis bellina.31th New Phytologist Symposium - Orchid symbioses: models for evolutionary ecology. May 14-16. University of Calabria, Rende, Italy.

  11. Chen, H.H.* 2012. Floral scent production in Phalaenopsis bellina. Twentith Symposium on Recent Advances in Cellular and Molecular Biology. February 7-8. Kaohsiung, Taiwan.

  12. Tsai, W.C., Hsiao, Y.Y., Chen, Y.W., Huang, S.C., Pan, Z.J., Chen, W.H., and Chen, H.H.* 2011. Characterization of Phalaenopsis transcriptome using massively parallel pyrosequencing. 20th World Orchid Conference. November 13-20. Singapore.
  13. Hsiao, Y.Y., Yao, S.H., Tsai, W.C. Hsieh, M.H., Lee, Y.I., Chen, W.H., and Chen, H.H.* 2011. Geranyl diphosphate synthese in Phalaenopsis bellina. 20th World Orchid Conference. November 13-20. Singapore.
  14. Chen, H.H.* 2011. Molecular Biology of Orchid Flower – with emphasis on Phalaenopsis. 20th World Orchid Conference. November 13-20. Singapore.

    C)eE�$�r$fareast-language:ZH-TW;mso-bidi-language: AR-SA'>Chen, H.H.* 2011. Geranyl diphosphate synthese in Phalaenopsis bellina. 20th World Orchid Conference. November 13-20. Singapore.
  15. Chen, H.H.* 2011. Current status of orchid genomics research. International Symposium on Orchid Molecular Markers and Genomics. November 10. Tainan. Taiwan.

  16. Chen, H.H.*, Tsai, W.C., Hsiao, Y.Y., Pan, Z.J., Hsu, C.C., Yang, Y.P., and Chen, W.H. 2010. Molecular biology of orchid flowers with emphasis on Phalaenopsis. Plant Biology 2010. Abstract Book, P71. Montréal, Canada. 
  17. Hsiao, Y.Y., Yao, S.H., Tsai, W.C., Hsieh, M.H., Lee, Y.I., Chen, W.H., and Chen, H.H.* 2010. The role of GDPS involved in the floral scent production in Phalaenopsis bellina (Orchid). Plant Biology 2010. Abstract Book, P67. Montréal, Canada.

  18. Hsiao, Y.Y., Tsai, W.C., Pan, Z.J., Huang, S.C., Chen, Y.W., and Chen, H.H.* 2010. Transcriptome of Phalaenopsis orchid revealed by next generation sequencing, 454 pyrosequencing. Eighteenth Symposium on Recent Advances in Cellular and Molecular Biology. Abstract Book, P313. Kenting, Taiwan.

  19. Chen, Y.W., Tsai, W.C., Hsiao, Y.Y., Pan, Z.J., Huang, S.C., Huang, C.H., Cheng, S.Y., and Chen, H.H.* 2010. Construction and functional characterization of the Phalaenopsis full-length cDNA encyclopedia. Eighteenth Symposium on Recent Advances in Cellular and Molecular Biology. Abstract Book, P244. Kenting, Taiwan.
  20. Hsiao, Y.Y. Tsai, W.C., Chen, W.H., and Chen, H.H.* 2010. A novel functional homodimer geranyl diphosphate synthase for scent production in Phalaenopsis bellina (Orchidaceae) flower. The First Orchid Symposium. Abstract Book, P61. Taichung, Taiwan. (Oral presentation)

  21. Tsai, W.C., Hsiao, Y.Y., Pan, Z.J., and Chen, H.H.* 2010. Molecular mechanism underlying orchid floral morphogenesis. The First Orchid Symposium. Abstract Book, P63. Taichung, Taiwan. (Oral presentation)
  22. Pan, Z.J., Tsai, W.C., Chen, W.H., and Chen, H.H.* 2010. Identification and characterization of SEP-like genes in Phalaenopsis. The First Orchid Symposium. Abstract Book, P116. Taichung, Taiwan.

  23. Luo, Y.R., Tsai, W.C., and Chen, H.H.* 2010. Characterization of AGL6-like genes involved in perianth development of orchids. The First Orchid Symposium. Abstract Book, P115. Taichung, Taiwan (壁報論文佳作獎).

  24. Chuang, Y.C., Hsiao, Y.Y., Tsai, W.C., and Chen, H.H.* 2010. Study of MYB factors involved in the regulating fragrance biosynthesis in Phalaenopsis bellina. The First Orchid Symposium. Abstract Book, P114. Taichung, Taiwan.

     

  25. Yang, Y.P., Hsiao, Y.Y., Tsai, W.C., Li, C.Y., Wu, T.S., Chen, W.H., Jeng, M.F., and Chen, H.H.* 2010. Cloning and functional characterization of sesquiterpene synthase in Phalaenopsis equestris S82-159. The First Orchid Symposium. Abstract Book, P113. Taichung, Taiwan.

  26. Chung, Y.L., Kuo, Y.T., Lee, Y.L., Chen, T.C., Hsu, C.C., Tsai, W.C., Chen, H.H.*, and Wu, W.L. 2010. A first survey of the orchid (Phalaenopsis equestris) genome composition through BAC end sequencing analysis. The First Orchid Symposium. Abstract Book, P100. Taichung, Taiwan. (壁報論文優勝獎)

  27. Wu, C.F., Cheng, H.Y., Tsai, W.C., Kuo, P.C., Chen, W.H., and Chen, H.H.* 2010. Identification and characterization of UDP-glucosyltransferase for major flavonoid and anthocyanin synthesis in Phalaenopsis orchids. The First Orchid Symposium. Abstract Book, P99. Taichung, Taiwan.

C.其他論文發表(專書編輯或專書章節作者)

  1. Tsai, W.C., Hsiao, Y.Y., Pan, Z.J., Chen, Y.W., and Chen, H.H.* 2011. The relationship between ethylene and orchid ovule development. In: W. H. Chen, and H. H. Chen (eds.) Orchid Biotechnology II. World Scientific Publishing Co. Singapore. pp 229-251.
  2. Hsiao, Y.Y., Tsai, W.C., Chen, W.H., and Chen, H.H.* 2011. Biosynthetic regulation of floral scent in Phalaenopsis. In: W. H. Chen, and H. H. Chen (eds.) Orchid Biotechnology II. World Scientific Publishing Co. Singapore. pp 145-180.

  3. Chen, W.H and Chen, H.H.* Orchid Biotechnology II, 2011. World Scientific Publishing Co., Singapore.

  4. Hsiao, Y.Y., Tsai, W.C., and Chen, H.H.* 2010. A novel functional geranyl diphosphate synthase for scent production in Phalaenopsis bellina flowers. In: Blanchard, M.C., Runkle, E.S., and Lee, Y.I. (eds.) Proceedings of the 1st International Orchid Symposium, Drukkerij Station Drukwerk, Netherlands, Acta Horticulture 878, pp 481-487.

  5. Tsai, W.C., Hsiao, Y.Y., Pan, Z. J., and Chen, H.H.* 2010. Molecular mechanisms underlying orchid floral morphogenesis. In: Blanchard, M.C., Runkle, E.S., and Lee, Y.I. (eds.) Proceedings of the 1st International Orchid Symposium, Drukkerij Station Drukwerk, Netherlands, Acta Horticulture 878, pp 115-123.

1.專利:研發成果智慧財產權及其應用績效

 

類別 專利名稱 國別 專利號碼 發明人 專利權人 專利核准日期
A 於蘭花中控制花發育之基因 中華民國 I 228511 陳虹樺 成功大學 1994/1/7
Genes Controlling Floral Development in Orchid 蔡文杰
  陳文輝
A   美國 7049489 陳虹樺 成功大學 1995/5/23
Genes Controlling Floral Development in Orchid 蔡文杰
  陳文輝
A 蝴蝶蘭花形決定及花朵壽命延長基因 中華民國 I 289143 陳虹樺 成功大學 1996/11/1
Dual functions of PeMADS6, aPISTALLATA/GLOBOSA- 蔡文杰
like gene, in Phalaenopsis equestris: petaloid formation and flower longevity extension 陳文輝
  李佩芳
A Viral vector for inducing gene inactivation of plants and application thereof 美國 7588935 葉信宏 國立台灣大學 2009/09/15~2026/05/23
陳虹樺
陸祥家
A 去氧核醣核酸聚合脢、編碼該去氧核醣核酸聚合脢之核酸分子及其應用 中華民國 I 326709 陳虹樺
鄭嘉雄
成功大學 2010/07/01~
2027/08/27
A 一種誘發植物產生基因不活化的病毒載體 中華民國 I 344478 葉信宏 國立台灣大學 2011/7/1
陳虹樺 ~
陸祥家 2025/10/12
A 促進植物產生香味之基因、蛋白質及方法 中華民國 I 361041 陳虹樺 成功大學 2012/04/01~
蕭郁芸 2028/7/20
蔡文杰  
陳文輝  
   
A Genes, proteins and methods promoting plants producing scent  美國 申請號碼: 陳虹樺 成功大學 申請中
096–077AP–US 蕭郁芸
  蔡文杰
  陳文輝

2技術移轉

技術名稱 授權單位 被授權單位 簽約日期
蘭花香水製程 成功大學 基龍米克斯生物科技公司 99年1月

 

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